eGFR - according to the CKD-EPI formula

The MDRD formula underestimates the glomerular filtration rate (GFR) in the higher range from about 60 ml / min / 1.73m 2 , while the CKD-EPI formula estimates the GFR more correctly in this range. Study results based on 8,254 patients show better agreement with reference methods in this area.

The difference is of particular relevance in patients with incipient kidney disease. Here the CKD-EPI formula enables a more correct estimate of the GFR. Ideally, the GFR in prevention is based on cystatin C, which, due to its biochemical properties, allows an even more reliable statement regarding the early detection or exclusion of an incipient kidney disease. Formula so that the use of the CKD-EPI formula does not bring any clinical benefits in these patients.

The formula was prepared by a research group of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), the National Institute of Diabetes and Digestive and Kidney Disease (NIDDKD).


 

eGFR - according to the CKD-EPI formula

The MDRD formula underestimates the glomerular filtration rate (GFR) in the higher range from about 60 ml / min / 1.73m 2 , while the CKD-EPI formula estimates the GFR more correctly in this range. Study results based on 8,254 patients show better agreement with reference methods in this area.

The difference is of particular relevance in patients with incipient kidney disease. Here the CKD-EPI formula enables a more correct estimate of the GFR. Ideally, the GFR in prevention is based on cystatin C, which, due to its biochemical properties, allows an even more reliable statement regarding the early detection or exclusion of an incipient kidney disease. Formula so that the use of the CKD-EPI formula does not bring any clinical benefits in these patients.

The formula was prepared by a research group of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), the National Institute of Diabetes and Digestive and Kidney Disease (NIDDKD).